Kristen Pauken

Kristen Pauken

Postdoctoral fellow
Kristen

Kristen received her Bachelor's of Science in Microbiology from Colorado State University, where she first discovered her passion for the immune system studying how sand fly saliva impacted innate immunity to Leishmania major. She then went on to receive her Ph.D. at the University of Minnesota studying PD-1-mediated regulation of autoreactive CD4+ T cells during Type 1 Diabetes. Kristen continued studying the PD-1 pathway at the University of Pennsylvania, examining how PD-1 blockade impacted exhausted CD8+ T cell responses. In the Sharpe lab, Kristen is combining her expertise in tolerance and exhaustion to study immune responses to cancer and basic mechanisms of PD-1-based immunotherapy in this setting. Outside of lab, Kristen enjoys running, cooking, and talking immunology with her husband.