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262. Girvin AM, Dal Canto MC, Rhee L, Salomon B, Sharpe A, et al. A critical role for 
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263. McAdam AJ, Farkash EA, Gewurz BE, Sharpe AH. B7 costimulation is critical for
antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host
response to vesicular stomatitis virus. Journal of virology. 2000; 74(1):203-8.
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264. Anderson DE, Sharpe AH, Hafler DA. The B7-CD28/CTLA-4 costimulatory pathways in
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265. Chen AI, McAdam AJ, Buhlmann JE, Scott S, Lupher ML Jr, et al. Ox40-ligand has a 
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266. Guttormsen HK, Sharpe AH, Chandraker AK, Brigtsen AK, Sayegh MH, et al. Cognate
stimulatory B-cell-T-cell interactions are critical for T-cell help recruited by 
glycoconjugate vaccines. Infection and immunity. 1999; 67(12):6375-84. PubMed
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267. Abbas AK, Sharpe AH. T-cell stimulation: an abundance of B7s. Nature medicine.
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268. Schweitzer AN, Sharpe AH. Mutual regulation between B7-1 (CD80) expressed on T
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269. Mandelbrot DA, Furukawa Y, McAdam AJ, Alexander SI, Libby P, et al. Expression of
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270. Ling V, Wu PW, Finnerty HF, Sharpe AH, Gray GS, et al. Complete sequence
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271. Chang TT, Jabs C, Sobel RA, Kuchroo VK, Sharpe AH. Studies in B7-deficient mice
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272. Oosterwegel MA, Mandelbrot DA, Boyd SD, Lorsbach RB, Jarrett DY, et al. The role 
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273. Humphries DE, Wong GW, Friend DS, Gurish MF, Qiu WT, et al. Heparin is essential 
for the storage of specific granule proteases in mast cells. Nature. 1999;
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274. Liang B, Gee RJ, Kashgarian MJ, Sharpe AH, Mamula MJ. B7 costimulation in the
development of lupus: autoimmunity arises either in the absence of B7.1/B7.2 or
in the presence of anti-b7.1/B7.2 blocking antibodies. Journal of immunology
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275. Lynch WP, Sharpe AH, Snyder EY. Neural stem cells as engraftable packaging lines 
can mediate gene delivery to microglia: evidence from studying retroviral
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276. Oosterwegel MA, Greenwald RJ, Mandelbrot DA, Lorsbach RB, Sharpe AH. CTLA-4 and T
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277. Blazar BR, Taylor PA, Panoskaltsis-Mortari A, Sharpe AH, Vallera DA. Opposing
roles of CD28:B7 and CTLA-4:B7 pathways in regulating in vivo alloresponses in
murine recipients of MHC disparate T cells. Journal of immunology (Baltimore, Md.
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278. Khattri R, Auger JA, Griffin MD, Sharpe AH, Bluestone JA. Lymphoproliferative
disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of
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279. Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, et al. p63 is essential for
regenerative proliferation in limb, craniofacial and epithelial development.
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280. La Motte RN, Sharpe AH, Bluestone JA, Mokyr MB. Host B7-1 and B7-2 costimulatory 
molecules contribute to the eradication of B7-1-transfected P815 tumor cells via 
a CD8+ T cell-dependent mechanism. Journal of immunology (Baltimore, Md. : 1950).
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281. Greenwald RJ, Urban JF, Ekkens MJ, Chen S, Nguyen D, et al. B7-2 is required for 
the progression but not the initiation of the type 2 immune response to a
gastrointestinal nematode parasite. Journal of immunology (Baltimore, Md. :
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282. Hernandez HJ, Sharpe AH, Stadecker MJ. Experimental murine schistosomiasis in the
absence of B7 costimulatory molecules: reversal of elicited T cell cytokine
profile and partial inhibition of egg granuloma formation. Journal of immunology 
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283. Judge TA, Wu Z, Zheng XG, Sharpe AH, Sayegh MH, et al. The role of CD80, CD86,
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survival. Journal of immunology (Baltimore, Md. : 1950). 1999; 162(4):1947-51.
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284. González-Cabrero J, Wise CJ, Latchman Y, Freeman GJ, Sharpe AH, et al.
CD48-deficient mice have a pronounced defect in CD4(+) T cell activation.
Proceedings of the National Academy of Sciences of the United States of America. 
1999; 96(3):1019-23. PubMed [journal] PMID: 9927686, PMCID: PMC15343

285. Mandelbrot DA, McAdam AJ, Sharpe AH. B7-1 or B7-2 is required to produce the
lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated
antigen 4 (CTLA-4). The Journal of experimental medicine. 1999; 189(2):435-40.
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286. La Motte RN, Sharpe AH, Bluestone JA, Mokyr MB. Importance of B7-1-expressing
host antigen-presenting cells for the eradication of B7-2 transfected P815 tumor 
cells. Journal of immunology (Baltimore, Md. : 1950). 1998; 161(12):6552-8.
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287. Rauschmayr-Kopp T, Williams IR, Borriello F, Sharpe AH, Kupper TS. Distinct roles
for B7 costimulation in contact hypersensitivity and humoral immune responses to 
epicutaneous antigen. European journal of immunology. 1998; 28(12):4221-7. PubMed
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288. Wang B, Wang N, Salio M, Sharpe A, Allen D, et al. Essential and partially
overlapping role of CD3gamma and CD3delta for development of alphabeta and
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289. McAdam AJ, Schweitzer AN, Sharpe AH. The role of B7 co-stimulation in activation 
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290. Schweitzer AN, Sharpe AH. Studies using antigen-presenting cells lacking
expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 
molecules during priming versus restimulation of Th2 but not Th1 cytokine
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291. Schweitzer AN, Sharpe AH. The complexity of the B7-CD28/CTLA-4 costimulatory
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292. Van Parijs L, Sethna MP, Schweitzer AN, Borriello F, Sharpe AH, et al. Functional
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293. Zheng XX, Sayegh MH, Zheng XG, Li Y, Linsley PS, et al. The role of donor and
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294. Reeves RH, Patch D, Sharpe AH, Borriello F, Freeman GJ, et al. The costimulatory 
genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3.
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295. Tivol EA, Boyd SD, McKeon S, Borriello F, Nickerson P, et al. CTLA4Ig prevents
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296. Borriello F, Lederer J, Scott S, Sharpe AH. MRC OX-2 defines a novel T cell
costimulatory pathway. Journal of immunology (Baltimore, Md. : 1950). 1997;
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297. Schweitzer AN, Borriello F, Wong RC, Abbas AK, Sharpe AH. Role of costimulators
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298. Borriello F, Sethna MP, Boyd SD, Schweitzer AN, Tivol EA, et al. B7-1 and B7-2
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299. Greenfield EA, Howard E, Paradis T, Nguyen K, Benazzo F, et al. B7.2 expressed by
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300. Yergeau DA, Hetherington CJ, Wang Q, Zhang P, Sharpe AH, et al. Embryonic
lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO
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301. Tivol EA, Schweitzer AN, Sharpe AH. Costimulation and autoimmunity. Current
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302. Coxon A, Rieu P, Barkalow FJ, Askari S, Sharpe AH, et al. A novel role for the
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303. Wang JH, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, et al. Selective defects in
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304. Lynch WP, Snyder EY, Qualtiere L, Portis JL, Sharpe AH. Late virus replication
events in microglia are required for neurovirulent retrovirus-induced spongiform 
neurodegeneration: evidence from neural progenitor-derived chimeric mouse brains.
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305. Wang Q, Stacy T, Miller JD, Lewis AF, Gu TL, et al. The CBFbeta subunit is
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306. Blazar BR, Sharpe AH, Taylor PA, Panoskaltsis-Mortari A, Gray GS, et al. Infusion
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graft-versus-host disease lethality in part via direct effects on CD4+ and CD8+ T
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307. Wang Q, Stacy T, Binder M, Marin-Padilla M, Sharpe AH, et al. Disruption of the
Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and
blocks definitive hematopoiesis. Proceedings of the National Academy of Sciences 
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308. Borriello F, Oliveros J, Freeman GJ, Nadler LM, Sharpe AH. Differential
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309. Thomis DC, Gurniak CB, Tivol E, Sharpe AH, Berg LJ. Defects in B lymphocyte
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310. Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, et al. Loss of
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311. Sharpe AH. Analysis of lymphocyte costimulation in vivo using transgenic and
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312. Perkins AC, Sharpe AH, Orkin SH. Lethal beta-thalassaemia in mice lacking the
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313. Johnson KA, Lerner CP, Di Lacio LC, Laird PW, Sharpe AH, et al. Transgenic mice
for the preparation of hygromycin-resistant primary embryonic fibroblast feeder
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314. Witke W, Sharpe AH, Hartwig JH, Azuma T, Stossel TP, et al. Hemostatic,
inflammatory, and fibroblast responses are blunted in mice lacking gelsolin.
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315. Prabhu Das MR, Zamvil SS, Borriello F, Weiner HL, Sharpe AH, et al. Reciprocal
expression of co-stimulatory molecules, B7-1 and B7-2, on murine T cells
following activation. European journal of immunology. 1995; 25(1):207-11. PubMed 
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316. Gurtner GC, Davis V, Li H, McCoy MJ, Sharpe A, et al. Targeted disruption of the 
murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and
placentation. Genes & development. 1995; 9(1):1-14. PubMed [journal] PMID:
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317. Jellis CL, Wang SS, Rennert P, Borriello F, Sharpe AH, et al. Genomic
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318. Borriello F, Freeman GJ, Edelhoff S, Disteche CM, Nadler LM, et al.
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319. Georgopoulos K, Bigby M, Wang JH, Molnar A, Wu P, et al. The Ikaros gene is
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320. Sethna MP, van Parijs L, Sharpe AH, Abbas AK, Freeman GJ. A negative regulatory
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321. Freeman GJ, Borriello F, Hodes RJ, Reiser H, Gribben JG, et al. Murine B7-2, an
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322. Freeman GJ, Borriello F, Hodes RJ, Reiser H, Hathcock KS, et al. Uncovering of
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323. Sharpe AH, Jaenisch R. Retroviral spongiform degenerative disease produced by the
murine neurotropic retrovirus Cas-Br-E. Developments in biological
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324. Lee KF, Li E, Huber LJ, Landis SC, Sharpe AH, et al. Targeted mutation of the
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325. Huszar D, Sharpe A, Hashmi S, Bouchard B, Houghton A, et al. Generation of
pigmented stripes in albino mice by retroviral marking of neural crest
melanoblasts. Development (Cambridge, England). 1991; 113(2):653-60. PubMed
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326. Huszar D, Sharpe A, Jaenisch R. Migration and proliferation of cultured neural
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327. Lee JS, Mullaney S, Bronson R, Sharpe AH, Jaenisch R, et al. Transplacental
antiretroviral therapy with 9-(2-phosphonylmethoxyethyl)adenine is embryotoxic in
transgenic mice. Journal of acquired immune deficiency syndromes. 1991;
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328. Weiher H, Noda T, Gray DA, Sharpe AH, Jaenisch R. Transgenic mouse model of
kidney disease: insertional inactivation of ubiquitously expressed gene leads to 
nephrotic syndrome. Cell. 1990; 62(3):425-34. PubMed [journal] PMID: 1696177

329. Sharpe AH, Hunter JJ, Chassler P, Jaenisch R. Role of abortive retroviral
infection of neurons in spongiform CNS degeneration. Nature. 1990;
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330. Ruprecht RM, Sharpe AH, Jaenisch R, Trites D. Analysis of
3'-azido-3'-deoxythymidine levels in tissues and milk by isocratic
high-performance liquid chromatography. Journal of chromatography. 1990;
528(2):371-83. PubMed [journal] PMID: 2384575

331. Wu H, Bateman JF, Schnieke A, Sharpe A, Barker D, et al. Human-mouse interspecies
collagen I heterotrimer is functional during embryonic development of Mov13
mutant mouse embryos. Molecular and cellular biology. 1990; 10(4):1452-60. PubMed
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332. Sugimoto M, Sharpe AH, Sato Y, Greene MI, Fields BN. Reovirus transport--studies 
using lymphocytosis promoting factor. Pathobiology : journal of immunopathology, 
molecular and cellular biology. 1990; 58(4):185-92. PubMed [journal] PMID:
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333. Compere SJ, Baldacci P, Sharpe AH, Thompson T, Land H, et al. The ras and myc
oncogenes cooperate in tumor induction in many tissues when introduced into
midgestation mouse embryos by retroviral vectors. Proceedings of the National
Academy of Sciences of the United States of America. 1989; 86(7):2224-8. PubMed
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334. Sharpe AH, Hunter JJ, Ruprecht RM, Jaenisch R. Maternal transmission of
retroviral disease and strategies for preventing infection of the neonate.
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335. Compere SJ, Baldacci PA, Sharpe AH, Jaenisch R. Retroviral transduction of the
human c-Ha-ras-1 oncogene into midgestation mouse embryos promotes rapid
epithelial hyperplasia. Molecular and cellular biology. 1989; 9(1):6-14. PubMed
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336. Sharpe AH, Hunter JJ, Ruprecht RM, Jaenisch R. Maternal transmission of
retroviral disease: transgenic mice as a rapid test system for evaluating
perinatal and transplacental antiretroviral therapy. Proceedings of the National 
Academy of Sciences of the United States of America. 1988; 85(24):9792-6. PubMed 
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337. Sharpe AH, Jaenisch R, Ruprecht RM. Retroviruses and mouse embryos: a rapid model
for neurovirulence and transplacental antiviral therapy. Science (New York,
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338. Wolf JL, Dambrauskas R, Sharpe AH, Trier JS. Adherence to and penetration of the 
intestinal epithelium by reovirus type 1 in neonatal mice. Gastroenterology.
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339. Gaulton GN, Sharpe AH, Chang DW, Fields BN, Greene MI. Syngeneic monoclonal
internal image anti-idiotopes as prophylactic vaccines. Journal of immunology
(Baltimore, Md. : 1950). 1986; 137(9):2930-6. PubMed [journal] PMID: 3020129

340. Sharpe AH, Gaulton GN, Ertl HC, Finberg RW, McDade KK, et al. Cell receptors for 
the mammalian reovirus. IV. Reovirus-specific cytolytic T cell lines that have
idiotypic receptors recognize anti-idiotypic B cell hybridomas. Journal of
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341. Sharpe AH, Fields BN. Pathogenesis of viral infections. Basic concepts derived
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342. Sharpe AH, Gaulton GN, McDade KK, Fields BN, Greene MI. Syngeneic monoclonal
antiidiotype can induce cellular immunity to reovirus. The Journal of
experimental medicine. 1984; 160(4):1195-205. PubMed [journal] PMID: 6332875,
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343. Sharpe AH, Fields BN. Reovirus inhibition of cellular RNA and protein synthesis: 
role of the S4 gene. Virology. 1982; 122(2):381-91. PubMed [journal] PMID:
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344. Sharpe AH, Chen LB, Fields BN. The interaction of mammalian reoviruses with the
cytoskeleton of monkey kidney CV-1 cells. Virology. 1982; 120(2):399-411. PubMed 
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345. Ahmed R, Canning WM, Kauffman RS, Sharpe AH, Hallum JV, et al. Role of the host
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346. Wolf JL, Rubin DH, Finberg R, Kauffman RS, Sharpe AH, et al. Intestinal M cells: 
a pathway for entry of reovirus into the host. Science (New York, N.Y.). 1981;
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347. Sharpe AH, Fields BN. Reovirus inhibition of cellular DNA synthesis: role of the 
S1 gene. Journal of virology. 1981; 38(1):389-92. PubMed [journal] PMID: 7241660,
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348. Sharpe AH, Chen LB, Murphy JR, Fields BN. Specific disruption of vimentin
filament organization in monkey kidney CV-1 cells by diphtheria toxin, exotoxin
A, and cycloheximide. Proceedings of the National Academy of Sciences of the
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349. Fields BN, Weiner HL, Drayna DT, Sharpe AH. The role of the reovirus
hemagglutinin in viral virulence. Annals of the New York Academy of Sciences.
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350. Mustoe TA, Ramig RF, Sharpe AH, Fields BN. Genetics of reovirus: identification
of the ds RNA segments encoding the polypeptides of the mu and sigma size
classes. Virology. 1978; 89(2):594-604. PubMed [journal] PMID: 716219

351. Mustoe TA, Ramig RF, Sharpe AH, Fields BN. A genetic map of reovirus. III.
Assignment of the double-stranded RNA-positive mutant groups A, B, and G to
genome segments. Virology. 1978; 85(2):545-56. PubMed [journal] PMID: 664215

352. Ramig RF, Mustoe TA, Sharpe AH, Fields BN. A genetic map of reovirus. II.
Assignment of the double-stranded RNA-negative mutant groups C, D, and E to
genome segments. Virology. 1978; 85(2):531-4. PubMed [journal] PMID: 664214

353. Sharpe AH, Ramig RF, Mustoe TA, Fields BN. A genetic map of reovirus. 1.
Correlation of genome RNAs between serotypes 1, 2, and 3. Virology. 1978;
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354. Sharpe A, Blumberg PM, Strominger JL. D-alanine carboxypeptidase and cell wall
cross-linking in Bacillus subtilis. Journal of bacteriology. 1974; 117(2):926-7. 
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355. The role of reovirus hemagglutinin in virulence
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. WHO Collaborating Centre for Collection and Evaluation of Data on Comparative
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356. Dendritic cells but not lymph node stroma initiate ileitis by expanding T cells
with gut-homing specificity upon PD-L1 blockade1
Journal of immunology (Baltimore, Md. : 1950).
My Bibliography [journal]