Publications by Year: 2021

2021
Schneider J, Rowe J, Garcia de Alba C, Kim C, Sharpe A, Haigis M. The aging lung: Physiology, disease, and immunity. Cell. 2021;184.
Braun D, Street K, Burke K, Cookmeyer D, Denize T, Pedersen CB, Gohil S, Schindler N, Pomerance L, Hirsch L, et al. Progressive immune dysfunction with advancing disease stage in renal cell carcinoma. Cancer Cell. 2021;39.
Lo J, Kawakubo M, Juneja V, Su M, Erlich T, LaFleur M, Kemény L, Rashid M, Malehmir M, Rabi S, et al. Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses. Science Translational Medicine. 2021;13 :eabd8636.
Pauken K, Torchia J, Chaudhri A, Sharpe A, Freeman G. Emerging concepts in PD-1 checkpoint biology. Seminars in Immunology. 2021;52 :101480.
Collier J, Weiss S, Pauken K, Sen D, Sharpe A. Not-so-opposite ends of the spectrum: CD8+ T cell dysfunction across chronic infection, cancer and autoimmunity. Nature Immunology. 2021;22 :1-11.
Pauken K, Shahid O, Lagattuta K, Mahuron K, Luber J, Lowe M, Huang L, Delaney C, Long J, Fung M, et al. Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment. Journal of Experimental Medicine. 2021;218.
Kuchroo J, Hafler D, Sharpe A, Lucca LE. The double-edged sword: Harnessing PD-1 blockade in tumor and autoimmunity. Science immunology. 2021;6 :eabf4034.